发表SCI收录论文100余篇,撰写肿瘤相关著作2部:
1. 《Tumor Immunology Cancer Vaccines》(2006 Elsvier)
2. 《Progress in Cancer Immunotherapy》 (2015, Springer)
代表作:
Molecular subgroups and B7-H4 expression levels predict responses to DC Vaccines in glioblastoma: an exploratory randomized phase II clinical trial. Accept. Cancer immunology immunotherapy. 2018 Accept
mTOR-mediated glycolysis contributes to the enhanced suppressive function of tumor-infiltrating monocytic myeloid derived suppressor cells. Cancer immunology immunotherapy. 2018 Accept
Glycocalyx-Mimicking Nanoparticles Improve Anti-PD-L1 Cancer Immunotherapy through Reversion of Tumor-Associated Macrophages. Biomacromolecules. 2018 Jun 11; 19(6):2098-2108.
MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors. Gastroenterology. 2018 Feb, 154(3): 637-651.
New Chimeric Antigen Receptor Design for Solid Tumors. Frontiers in Immunology (Front Immunol). 2017 Dec 22, 8(1934): 1-9.
MiR-15a/16 deficiency enhances anti-tumor immunity of glioma-infiltrating CD8+ T cells through targeting mTOR. Int J Cancer. 2017 Nov 15, 141(10): 2082-2092.
Bifunctional HER2/CD3 RNA-engineered CART-like Human T Cells Specifically Eliminate HER2+ Gastric Cancer. Cell Res. 2016 Jul, 26(7): 850-853.
Low Percentage of CD24hiCD27+CD19+ B Cells Decelerates Gastric Cancer Progression in XELOX-treated Patients. Int Immunopharmacol. 2015 Jun, 26(2): 322-327.
Pseudomonas aeruginosa Mannose-Sensitive Hemagglutinin Promotes T-Cell Response via Toll-Like Receptor 4–Mediated Dendritic Cells to Slow Tumor Progression in Mice. J Pharmacol Exp Ther. 2014 May, 349(2): 279-287. (Global Medical Discovery)
Systemic Injection of TLR1/2 Agonist Improves Adoptive Antigen specific T Cell Therapy in Glioma-Bearing Mice. Clin Immunol. 2014 Sep, 154(1): 26-36.
Mouse glioma immunotherapy mediated by A2B5+ GL261 cell lysate-pulsed dendritic cells. J Neurooncol, 2014 Feb, 116(3): 497-504.
Low-dose Curcumin Leads to the Inhibition of Tumor Growth via Enhancing CTL-mediated Antitumor Immunity. Int Immunopharmacol. 2011 Sep, 11(9): 1234-1240.
TLR1/TLR2 Agonist Induces Tumor Regression by Reciprocal Modulation of Effector and Regulatory T Cells. J Immunol. 2011 Feb 15, 186(4):1963-1969. (Faculty 1000)
Cai Y, Xiong S, Zheng Y, Luo F, Jiang P, Chu Y. Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancer model by boosting the interaction between TSLC1 and CRTAM. Cell Mol Immunol. 2011 Jul, 8(4): 359-367.
授权发明专利5项:
1. 一种高效制备CIK的方法
2. 一种冻存细胞的方法
3. 一种DC细胞的快速制备方法
4. 一种铜绿假单胞菌MSHA菌毛株肿瘤疫苗及其制备方法
5. 一种携带抗Her2CD3双特异性功能蛋白的人T细胞制备
复旦大学生物治疗研究中心
地址:复旦大学 枫林校区 东安路130号西13号楼925室 邮编:200032
电话:021-54237769
© Copyright 2018 复旦大学生物治疗研究中心 - All rights reserved.